Simon Taylor Selected Research

Proteins (Proteins, Gene)

1/2021	Discovery of a Novel Bromodomain and Extra Terminal Domain (BET) Protein Inhibitor, I-BET282E, Suitable for Clinical Progression.
10/2020	Design and Synthesis of a Highly Selective and In Vivo-Capable Inhibitor of the Second Bromodomain of the Bromodomain and Extra Terminal Domain Family of Proteins.
1/2020	Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation.
8/2011	Molecular characterization of a long range haplotype affecting protein yield and mastitis susceptibility in Norwegian Red cattle.

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Simon Taylor Research Topics

Disease

4	Neoplasms (Cancer) 01/2020 - 10/2014
3	Uveitis 11/2019 - 01/2018
2	Inflammation (Inflammations) 10/2020 - 10/2014
2	Retinal Vasculitis 11/2019 - 10/2019
2	Iridocyclitis 11/2019 - 10/2019
2	Chorioretinitis 11/2019 - 10/2019
2	Conjunctivitis 11/2019 - 10/2019
2	Optic Neuritis (Retrobulbar Neuritis) 11/2019 - 10/2019
2	Scleritis (Episcleritis) 11/2019 - 10/2019
2	Anterior Uveitis 11/2019 - 10/2019
2	Keratitis 11/2019 - 10/2019
2	Retinal Vein Occlusion 11/2019 - 10/2019
2	Relapsing-Remitting Multiple Sclerosis 02/2016 - 10/2011
1	Frontal Sinusitis 11/2022
1	Disease Progression 01/2021
1	Dementia (Dementias) 01/2019
1	Warts (Wart) 01/2018
1	Infections 01/2018
1	Optic Nerve Diseases (Optic Neuropathy) 01/2017
1	Exophthalmos (Proptosis) 01/2017
1	Graves Ophthalmopathy 01/2017
1	Macular Edema 06/2016
1	Schizophrenia (Dementia Praecox) 04/2016
1	Leukemia 12/2015
1	Genetic Translocation (Chromosomal Translocation) 12/2015
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 12/2015
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 10/2015
1	Breast Neoplasms (Breast Cancer) 01/2015
1	Triple Negative Breast Neoplasms 01/2015
1	Multiple Sclerosis 12/2014
1	Neuroblastoma 10/2014
1	Septic Shock (Toxic Shock Syndrome) 10/2014
1	Sclerosis 07/2012
1	Mastitis 08/2011
1	Hypertension (High Blood Pressure) 06/2011
1	Experimental Arthritis 06/2011
1	Bradycardia 06/2011
1	Entropion 05/2008
1	Hemorrhage 05/2008

Drug/Important Bio-Agent (IBA)

5	Fingolimod Hydrochloride (FTY720)FDA Link 02/2016 - 06/2011
4	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2011
2	Dexamethasone (Maxidex)FDA LinkGeneric 11/2019 - 10/2019
2	Retinaldehyde (Retinal)IBA 11/2019 - 10/2019
2	Biomarkers (Surrogate Marker)IBA 01/2019 - 10/2015
2	Pharmaceutical PreparationsIBA 01/2015 - 12/2014
2	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 12/2014 - 07/2012
1	HydrogelsIBA 11/2022
1	Messenger RNA (mRNA)IBA 01/2018
1	Antiviral Agents (Antivirals)IBA 01/2018
1	molibresibIBA 01/2018
1	Adrenal Cortex Hormones (Corticosteroids)IBA 06/2016
1	SteroidsIBA 06/2016
1	Antidepressive Agents (Antidepressants)IBA 04/2016
1	Antipsychotic Agents (Antipsychotics)IBA 04/2016
1	Citalopram FDA LinkGeneric 04/2016
1	I-CBP112IBA 12/2015
1	Doxorubicin (Adriamycin)FDA LinkGeneric 12/2015
1	Histone Acetyltransferases (Histone Acetyltransferase)IBA 12/2015
1	Interleukin-17 (Interleukin 17)IBA 10/2015
1	Interleukin-23 (Interleukin 23)IBA 10/2015
1	Estrogens (Estrogen)FDA Link 01/2015
1	ErbB Receptors (EGF Receptor)IBA 01/2015
1	Progesterone FDA LinkGeneric 01/2015
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2015
1	Phosphates (Orthophosphate)IBA 12/2014
1	Sphingosine-1-Phosphate ReceptorsIBA 12/2014
1	1,2,3,4-tetrahydroquinolineIBA 10/2014
1	Bromodomain Containing ProteinsIBA 10/2014
1	Apolipoprotein A-I (Apolipoprotein A1)IBA 10/2014
1	Immunologic Factors (Immunomodulators)IBA 07/2012
1	Milk Proteins (Milk Protein)IBA 08/2011
1	compound 20IBA 06/2011
1	Keratins (Keratin)IBA 05/2008

Therapy/Procedure

2	Therapeutics 12/2015 - 01/2015
1	Glycemic Control 01/2018
1	Decompression 01/2017